Buprenorphine for Opioid Use Disorder - Advisory CoverSAMHSA has released a new advisory about medication-assisted treatment for opioid use disorders. The advisory reviews information on the use of buprenorphine as a treatment.  It includes information on new formulations of buprenorphine, its effectiveness and safety, contraindications and cautions (including medication interactions), treatment monitoring, and indications of misuse.